HCV-IN-39

HCV-IN-39 (Compound 18a) is a potent hepatitis C virus (HCV) nucleoside inhibitor with EC50 values of 0.644, 0.952 and 0.154 μM against GT1a, GT1b and GT1b CES1 replicons[1].

Product Specifications

CAS Number

[2087916-31-0]

UNSPSC

12352005

Target

HCV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/hcv-in-39.html

Solubility

10 mM in DMSO

Smiles

CCOC(C(C)(N[P@](OC[C@H]1O[C@H]([C@](Br)([C@@H]1O)Cl)N2C=CC(NC2=O)=O)(OC3=CC=CC=C3)=O)C)=O

Molecular Formula

C21H26BrClN3O9P

Molecular Weight

610.78

References & Citations

[1]Chris Krueger A, et al. Synthesis and evaluation of 2'-dihalo ribonucleotide prodrugs with activity against hepatitis C virus. Bioorg Med Chem. 2020 Jan 1;28 (1) :115208.