DPPY
Product Specifications
UNSPSC Description
DPPY (compound 6) is a potent PTK inhibitor with IC50 values of [1].
Target Antigen
Btk; EGFR; JAK
Type
Reference compound
Related Pathways
Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/dppy.html
Solubility
10 mM in DMSO
Smiles
C=CC(NC1=CC(NC2=NC(NC3=CC=C(C=C3)NC(CN4CCOCC4)=O)=NC=C2Cl)=CC=C1)=O
Molecular Weight
507.97
References & Citations
[1]Zhu Y, et al. Synthesis and biological activity of thieno[3,2-d]pyrimidines as potent JAK3 inhibitors for the treatment of idiopathic pulmonary fibrosis. Bioorg Med Chem. 2020 Jan 15;28(2):115254.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-147741/DPPY-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-147741/
Clinical Information
No Development Reported
CAS Number
2095883-62-6
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