WEHI-150
WEHI-150 is a replica of mitoxantrone, is a portent DNA interstrand crosslink[1].
Product Specifications
CAS Number
[70492-21-6]
UNSPSC
12352005
Target
DNA Alkylator/Crosslinker
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/wehi-150.html
Solubility
10 mM in DMSO
Smiles
NCCNCCNC1=CC=C(C2=C1C(C3=C(C=CC(O)=C3C2=O)O)=O)NCCNCCN
Molecular Formula
C22H30N6O4
Molecular Weight
442.51
References & Citations
[1]Pumuye PP, et al. Formaldehyde-activated WEHI-150 induces DNA interstrand crosslinks with unique structural features. Bioorg Med Chem. 2020 Feb 1;28 (3) :115260.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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