WEHI-150

WEHI-150 is a replica of mitoxantrone, is a portent DNA interstrand crosslink[1].

Product Specifications

CAS Number

[70492-21-6]

UNSPSC

12352005

Target

DNA Alkylator/Crosslinker

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/wehi-150.html

Solubility

10 mM in DMSO

Smiles

NCCNCCNC1=CC=C(C2=C1C(C3=C(C=CC(O)=C3C2=O)O)=O)NCCNCCN

Molecular Formula

C22H30N6O4

Molecular Weight

442.51

References & Citations

[1]Pumuye PP, et al. Formaldehyde-activated WEHI-150 induces DNA interstrand crosslinks with unique structural features. Bioorg Med Chem. 2020 Feb 1;28 (3) :115260.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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