GABAA receptor agonist 2
Product Specifications
UNSPSC Description
GABAA receptor agonist 2 (compound 4c) is a potent GABAA receptor agonist. GABAA receptor agonist 2 shows anti-depression activities in classical mouse models of depression of FST and TST. GABAA receptor agonist 2 binds at the GABA binding site of GABAA receptor in order to produce GABAergic effects. GABAA receptor agonist 2 has the potential for the research of depression[1].
Target Antigen
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/gabaa-receptor-agonist-2.html
Solubility
10 mM in DMSO
Smiles
C[C@]12CC[C@@H](O3)[C@@]3(C)CC[C@@H](OC(C)=O)[C@@]4(C)CC[C@](C(C)C)(O4)C[C@@H]1O2
Molecular Weight
380.52
References & Citations
[1]Ur Rehman N, et al. Incensole derivatives from frankincense: Isolation, enhancement, synthetic modification, and a plausible mechanism of their anti-depression activity. Bioorg Chem. 2022 Sep;126:105900.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-147736/GABAA-receptor-agonist-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-147736/
Clinical Information
No Development Reported
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