SEH inhibitor-5
SEH inhibitor-5 (compound D016) is a potent sEH (soluble epoxide hydrolase) inhibitor with an IC50 value of 0.1 nM[1].
Product Specifications
CAS Number
2752467-28-8
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/seh-inhibitor-5.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=NC2=CC=C(C=C2S1)N(C(NC3=CC=C(C=C3)Cl)=O)CCN4CCOCC4)NC5=CC=C(C=C5)Cl
Molecular Formula
C27H26Cl2N6O3S
Molecular Weight
585.50
References & Citations
[1]Han Y, et al. Ligand-based optimization to identify novel 2-aminobenzo[d]thiazole derivatives as potent sEH inhibitors with anti-inflammatory effects. Eur J Med Chem. 2021 Feb 15;212:113028.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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