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sEH inhibitor-4

Product Specifications

UNSPSC Description

Intensive structural modification resulted in the identification of compound B15 as an effective sEH inhibitor with a value of 0.03 ± 0.01 nm, and the presence of soluble epoxide hydrolase (SEH) can reduce inflammation and pain.

Target Antigen

Epoxide Hydrolase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/seh-inhibitor-4.html

Solubility

10 mM in DMSO

Smiles

CC1=C(C=CC(C(NC2=CC=C(C=C2)Cl)=O)=C1)N(C(NC3=CC=C(C=C3)Cl)=O)CCN4CCOCC4

Molecular Weight

527.44

References & Citations

[1]Tian Y,et al. Synthesis and biological evaluation of new series of benzamide derivatives containing urea moiety as sEH inhibitors. Bioorg Med Chem Lett. 2022 Aug 15;70:128805.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-147732/sEH-inhibitor-4-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-147732/

Clinical Information

No Development Reported

CAS Number

2851838-08-7

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