UIAA-II-232

UIAA-II-232 (compound 19b) is a potent DNA gyrase catalytic inhibitor with an IC50 value of 3.5 µM[1].

Product Specifications

CAS Number

[2428407-03-6]

UNSPSC

12352005

Target

DNA/RNA Synthesis

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/uiaa-ii-232.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=C2N(N=C1)C(N(CC)C3=C2C=C(F)C(N4C[C@H](CN)CC4)=C3)=O)OCC

Molecular Formula

C20H24FN5O3

Molecular Weight

401.43

References & Citations

[1]Aguirre AL, et al. Identification of an ethyl 5,6-dihydropyrazolo[1,5-c]quinazoline-1-carboxylate as a catalytic inhibitor of DNA gyrase. Bioorg Med Chem. 2020 May 15;28 (10) :115439.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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