UIAA-II-232
UIAA-II-232 (compound 19b) is a potent DNA gyrase catalytic inhibitor with an IC50 value of 3.5 µM[1].
Product Specifications
CAS Number
2428407-03-6
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/uiaa-ii-232.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C2N(N=C1)C(N(CC)C3=C2C=C(F)C(N4C[C@H](CN)CC4)=C3)=O)OCC
Molecular Formula
C20H24FN5O3
Molecular Weight
401.43
References & Citations
[1]Aguirre AL, et al. Identification of an ethyl 5,6-dihydropyrazolo[1,5-c]quinazoline-1-carboxylate as a catalytic inhibitor of DNA gyrase. Bioorg Med Chem. 2020 May 15;28 (10) :115439.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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