HIV-1 inhibitor-39
HIV-1 inhibitor-39 (compound 3c) is a potent HIV-1 inhibitor with an EC50 of >112.88 µM. HIV-1 inhibitor-39 shows anti-RT (HIV-1 reverse transcriptase) activities with an IC50 of 15.75 µM. HIV-1 inhibitor-39 shows cytotoxicity for MT-4 cells with an CC50 of 112.9 µM[1].
Product Specifications
CAS Number
[2414099-82-2]
UNSPSC
12352005
Target
HIV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/hiv-1-inhibitor-39.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC=C(S(=O)(C)=O)C=C1)CSC2=NN=C(N3C(C4=CC=CC(Cl)=C4)SCC3=O)S2
Molecular Formula
C20H17ClN4O4S4
Molecular Weight
541.09
References & Citations
[1]Buemi MR, et al. Inhibition of HIV-1 RT activity by a new series of 3- (1,3,4-thiadiazol-2-yl) thiazolidin-4-one derivatives. Bioorg Med Chem. 2020 Apr 15;28 (8) :115431.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HIV-1
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