α-Amylase/α-Glucosidase-IN-1
α-Amylase/α-Glucosidase-IN-1 (compound 33) is a potent α-amylase/α-glucosidase inhibitor with IC50s of 2.01, 2.09 µM for α-amylase and α-glucosidase, respectively. Kinetic studies predict that α-Amylase/α-Glucosidase-IN-1 has the potential of anti hyperglycemia[1].
Product Specifications
CAS Number
[329783-03-1]
UNSPSC
12352005
Target
Glycosidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/α-amylase-α-glucosidase-in-1.html
Solubility
10 mM in DMSO
Smiles
C12=C(NC(/C=N/N3C=NN=C3)=C2)C=CC=C1
Molecular Formula
C11H9N5
Molecular Weight
211.22
References & Citations
[1]Yeye EO, et al. Syntheses, in vitro α-amylase and α-glucosidase dual inhibitory activities of 4-amino-1,2,4-triazole derivatives their molecular docking and kinetic studies. Bioorg Med Chem. 2020 Jun 1;28 (11) :115467.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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