α-Amylase/α-Glucosidase-IN-1

α-Amylase/α-Glucosidase-IN-1 (compound 33) is a potent α-amylase/α-glucosidase inhibitor with IC50s of 2.01, 2.09 µM for α-amylase and α-glucosidase, respectively. Kinetic studies predict that α-Amylase/α-Glucosidase-IN-1 has the potential of anti hyperglycemia[1].

Product Specifications

CAS Number

[329783-03-1]

UNSPSC

12352005

Target

Glycosidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/α-amylase-α-glucosidase-in-1.html

Solubility

10 mM in DMSO

Smiles

C12=C(NC(/C=N/N3C=NN=C3)=C2)C=CC=C1

Molecular Formula

C11H9N5

Molecular Weight

211.22

References & Citations

[1]Yeye EO, et al. Syntheses, in vitro α-amylase and α-glucosidase dual inhibitory activities of 4-amino-1,2,4-triazole derivatives their molecular docking and kinetic studies. Bioorg Med Chem. 2020 Jun 1;28 (11) :115467.