PIN1 inhibitor 2
PIN1 inhibitor 2 (compound 12) is a potent PIN1 inhibitor. PIN1 inhibitor 2 shows antitumor activity with an IC50 of 9.55 µM for MCF7 cells. PIN1 inhibitor 2 has the potential for the research of breast cancer[1].
Product Specifications
CAS Number
2417101-28-9
UNSPSC
12352005
Target
MicroRNA
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pin1-inhibitor-2.html
Solubility
10 mM in DMSO
Smiles
CC1=C(C=C2NC(CSC(N3CCCCC3)=S)=NC2=C1)C
Molecular Formula
C16H21N3S2
Molecular Weight
319.49
References & Citations
[1]Nashaat S, et al. Synthesis, state-of-the-art NMR-binding and molecular modeling study of new benzimidazole core derivatives as Pin1 inhibitors: Targeting breast cancer. Bioorg Med Chem. 2020 Jun 1;28 (11) :115495.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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