Aurora kinase inhibitor-9
Product Specifications
UNSPSC Description
Aurora kinase inhibitor-9 (compound 9d) is a potent AURKA/B dual aurora kinase inhibitor with IC50s of 0.093, 0.09 µM for Aurora A, Aurora B, respectively. Aurora kinase inhibitor-9 shows broad spectrum anti-proliferative activity[1].
Target Antigen
Aurora Kinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Epigenetics
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/aurora-kinase-inhibitor-9.html
Solubility
10 mM in DMSO
Smiles
CCOC(C1=C(C2=C(C=C(C=C2N=C1)Cl)Cl)NC3=CC(S(=O)(NC)=O)=CC=C3)=O
Molecular Weight
454.33
References & Citations
[1]Al-Sanea MM, et al. Sulfonamide-based 4-anilinoquinoline derivatives as novel dual Aurora kinase (AURKA/B) inhibitors: Synthesis, biological evaluation and in silico insights. Bioorg Med Chem. 2020 Jul 1;28(13):115525.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-147703/Aurora-kinase-inhibitor-9-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-147703/
Clinical Information
No Development Reported
CAS Number
2419107-09-6
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS7252477-01 48 Well
Chicken Myeloid differentiation primary response protein MyD88 (MYD88) ELISA Kit
Ask
View Details MBS7252477-02 96 Well
Chicken Myeloid differentiation primary response protein MyD88 (MYD88) ELISA Kit
Ask
View Details MBS7252477-03 5x 96 Well
Chicken Myeloid differentiation primary response protein MyD88 (MYD88) ELISA Kit
Ask
View Details