BB 0305179
Product Specifications
UNSPSC Description
BB 0305179 (compound 59) is a potent anti-prion agent, with an IC50 of 4.7 μM. BB 0305179 inhibits the toxicity of a specific PrP mutant carrying a deletion in the hydrophobic domain [1]. BB 0305179 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Infection; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bb-0305179.html
Solubility
10 mM in DMSO
Smiles
O[C@]1(CCCC[C@@H]1NCC2CCCCC2)C#CC3=CC=CC=C3
Molecular Weight
311.46
References & Citations
[1]Altieri A, et al. Generation, optimization and characterization of novel anti-prion compounds. Bioorg Med Chem. 2020 Nov 1;28(21):115717.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-147702/BB-0305179-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-147702/
Clinical Information
No Development Reported
CAS Number
2512200-83-6
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