Ibodutant
Product Specifications
UNSPSC Description
Ibodutant (MEN 15596) is a potent and selective tachykinin NK2 receptor antagonist with a pKi of 10.1.
Target Antigen
Neurokinin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Neurological Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/MEN_15596.html
Solubility
10 mM in DMSO
Smiles
CC1=CC2=C(C=C(C(NC3(CCCC3)C(N[C@@]([H])(C(NCC4CCN(CC5CCOCC5)CC4)=O)CC6=CC=CC=C6)=O)=O)S2)C=C1
Molecular Weight
644.87
References & Citations
[1]Cialdai C, et al. MEN15596, a novel nonpeptide tachykinin NK2 receptor antagonist. Eur J Pharmacol. 2006 Nov 7;549(1-3):140-8.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-14770/Ibodutant-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-14770/
Clinical Information
Phase 3
CAS Number
522664-63-7
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