Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

C-Met-IN-11

C-Met-IN-11 (compound 3) is a potent c-MET and VEGFR-2 inhibitor, with IC50 values of 41.4 and 71.1 nM, respectively[1].

Product Specifications

CAS Number

1446324-05-5

UNSPSC

12352005

Target

C-Met/HGFR; VEGFR

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/c-met-in-11.html

Solubility

10 mM in DMSO

Smiles

COC1=CC2=NC=CC(OC3=C(C=C(C=C3)NC4=C5C(C(C6=CC=C(C=C6)F)=CNC5=CC=N4)=O)F)=C2C=C1

Molecular Formula

C30H20F2N4O3

Molecular Weight

522.50

References & Citations

[1]Xu H, et al. Discovery of N-substituted-3-phenyl-1,6-naphthyridinone derivatives bearing quinoline moiety as selective type II c-Met kinase inhibitors against VEGFR-2. Bioorg Med Chem. 2020 Jun 15;28 (12) :115555.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

VEGFR2/KDR/Flk-1

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

CF®647 Goat Anti-Mouse IgG3 (γ3), 2mg/mL
#20930-50uL 1x 50 µL

CF®647 Goat Anti-Mouse IgG3 (γ3), 2mg/mL

Sign In for Pricing
View Details
ERG Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI6A4]
TA506078AM 100 µL

ERG Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI6A4]

Sign In for Pricing
View Details
SUGT1 Mouse Monoclonal Antibody [Clone ID: OTI10A9]
CF810098 100 µg

SUGT1 Mouse Monoclonal Antibody [Clone ID: OTI10A9]

Sign In for Pricing
View Details
3-Aminopropyl-24,25-dihydroxy Vitamin D3
TRC-A628330-5MG 5 mg

3-Aminopropyl-24,25-dihydroxy Vitamin D3

Sign In for Pricing
View Details
FKBP11 (NM_016594) Human Recombinant Protein
TP306481L 1 mg

FKBP11 (NM_016594) Human Recombinant Protein

Sign In for Pricing
View Details
4,4',4''-Tri-tert-butyl-2,2':6',2''-terpyridine
TRC-T115090-10MG 10 mg

4,4',4''-Tri-tert-butyl-2,2':6',2''-terpyridine

Sign In for Pricing
View Details