Photosensitizer-2
Photosensitizer-2 (compound 1) is a organic D-π-A sensitizer against phototoxicity. Photosensitizer-2 contains an acrylic acid moiety that exerts high levels of phototoxicity. Photosensitizer-2 shows antitumor activity against HeLa cells, with IC50 values of 20.9 ± 4.5 μM (dark) and 0.046 ± 0.012 μM (irradiation), respectively[1].
Product Specifications
CAS Number
2138330-43-3
UNSPSC
12352005
Target
Photosensitizer
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/photosensitizer-2.html
Solubility
10 mM in DMSO
Smiles
O=C(/C=C/C1=CC=C(S1)C2=CC=C(S2)C3=CC=C(C=C3)N(C4=CC=CC=C4)C5=CC=CC=C5)O
Molecular Formula
C29H21NO2S2
Molecular Weight
479.61
References & Citations
[1]Fuse S, Moriya W, Sato S, Nakamura H. Investigation into the influence of an acrylic acid acceptor in organic D-π-A sensitizers against phototoxicity. Bioorg Med Chem. 2020 Jul 1;28 (13) :115558.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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