FGFR-IN-3

FGFR-IN-3 (compound 6) is an orally active, potent and BBB-penetrated FGFR (fibroblast growth factor receptor) modulator. FGFR-IN-3 shows neuroprotective activity. FGFR-IN-3 can be used for neurodegenerative diseases research[1].

Product Specifications

CAS Number

[2488762-63-4]

UNSPSC

12352005

Target

FGFR

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/fgfr-in-3.html

Solubility

10 mM in DMSO

Smiles

CC1=NC(OCC(N(C2CCN(CC2)CC3CC3(F)F)C)=O)=NC(C)=C1N

Molecular Formula

C18H27F2N5O2

Molecular Weight

383.44

References & Citations

[1]Sakai H, et al. Fibroblast growth factor receptor modulators employing diamines with reduced phospholipidosis-inducing potential. Bioorg Med Chem. 2020 Jul 15;28 (14) :115562.