CB 168
CB 168 is a potent and selective aminoacyl-sulfamoyl aryltetrazole inhibitor targeting isoleucyl-tRNA synthetase (IleRS) [1].
Product Specifications
CAS Number
[1241942-59-5]
UNSPSC
12352005
Target
Aminoacyl-tRNA Synthetase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/cb-168.html
Solubility
10 mM in DMSO
Smiles
CC[C@H](C)[C@H](N)C(NS(OC[C@H]([C@H]([C@H]1O)O)O[C@H]1CCN2N=C(C3=CC=CC=C3)N=N2)(=O)=O)=O
Molecular Formula
C20H30N6O7S
Molecular Weight
498.55
References & Citations
[1]De Ruysscher D, et al. Phenyltriazole-functionalized sulfamate inhibitors targeting tyrosyl- or isoleucyl-tRNA synthetase. Bioorg Med Chem. 2020 Aug 1;28 (15) :115580.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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