α-Synuclein inhibitor 5
Product Specifications
UNSPSC Description
α-Synuclein inhibitor 5 (compound 4aa) is a potent and BBB-penetrated inhibitor of α-Synuclein (α-Syn) aggregation, with an IC50 of 1.22 μM and inhibition ratio at 30 μM of 94.3%[1].
Target Antigen
α-synuclein
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/α-synuclein-inhibitor-5.html
Solubility
10 mM in DMSO
Smiles
CC1=CC=C(C=C1)S(=O)(NC2=CC=C(C=C2)NC(C3=CC(O)=C(C(O)=C3)O)=O)=O
Molecular Weight
414.43
References & Citations
[1]Chen L, et al. Amide derivatives of Gallic acid: Design, synthesis and evaluation of inhibitory activities against in vitro α-synuclein aggregation. Bioorg Med Chem. 2020 Aug 1;28(15):115596.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-147667/α-Synuclein-inhibitor-5-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-147667/
Clinical Information
No Development Reported
CAS Number
2489813-11-6
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
