Serum thymic factor (acetate)

Serum thymic factor acetate (Thymulin acetate) is the acetate salt form of Serum thymic factor (HY-P3206) . Serum thymic factor acetate is a zinc-dependent immunomodulatory peptide hormone, which can be produced by the thymic epithelial cells. Serum thymic factor acetate stimulates the release of hormones from the pituitary gland, exhibits hypophysiotropic activity. Serum thymic factor acetate protects rats from Cephaloridine (HY-B2072) -induced nephrotoxicity by inhibiting ERK activation. Serum thymic factor acetate exhibits anti-diabetic, anti-inflammatory and analgesic effects. Serum thymic factor acetate can be used in research about endocrine, reproductive, neurodegenerative and inflammatory diseases[1][2][3][4].

Product Specifications

CAS Number

[125117-65-9]

Product Name Alternative

Thymulin (acetate) ; Thymic factor (acetate)

UNSPSC

12352209

Target

ERK

Type

Peptides

Related Pathways

MAPK/ERK Pathway; Stem Cell/Wnt

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology; Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/serum-thymic-factor-acetate.html

Purity

99.62

Solubility

H2O : ≥ 100 mg/mL

Smiles

NC(C[C@@H](C(O)=O)NC([C@H](CO)NC(CNC(CNC([C@H](CCC(N)=O)NC([C@H](CO)NC([C@H](CCCCN)NC([C@H](C)NC([C@@H]1CCC(N1)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O.CC(O)=O

Molecular Formula

C35H58N12O17

Molecular Weight

918.91

References & Citations

[1]Pardo J, et al. Physiology, molecular biology and therapeutic potential of the thymic peptide thymulin[J]. Physiological Mini Reviews (PMR), 2012, 6.|[2]Dardenne M, et al. Role of thymulin or its analogue as a new analgesic molecule. Ann N Y Acad Sci. 2006 Nov;1088:153-63.|[3]Kohda Y, et al. Protective effect of serum thymic factor, FTS, on cephaloridine-induced nephrotoxicity in rats. Biol Pharm Bull. 2005 Nov;28 (11) :2087-91.|[4]Mizutani M, et al. In vivo administration of serum thymic factor (FTS) prevents EMC-D virus-induced diabetes and myocarditis in BALB/cAJcl mice. Arch Virol. 1996;141 (1) :73-83.