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Aminoacyl tRNA synthetase-IN-2

Aminoacyl tRNA synthetase-IN-2 (Compound 14) is an aminoacyl-tRNA synthetase (aaRS) inhibitor. Aminoacyl tRNA synthetase-IN-2 can be used for development of a new family of antibiotics[1].

Product Specifications

CAS Number

93218-59-8

UNSPSC

12352005

Target

Aminoacyl-tRNA Synthetase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/aminoacyl-trna-synthetase-in-2.html

Solubility

10 mM in DMSO

Smiles

O=C(O)[C@H](NC([C@@H](N)CO)=O)[C@@H]([C@@H]1[C@H](O)[C@@H](O)[C@H](N(C(N2C)=O)C=CC2=O)S1)O

Molecular Formula

C15H22N4O9S

Molecular Weight

434.42

References & Citations

[1]Gadakh B, et al. Synthesis and structural insights into the binding mode of the albomycin δ1 core and its analogues in complex with their target aminoacyl-tRNA synthetase. Bioorg Med Chem. 2020 Sep 1;28 (17) :115645.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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