Aminoacyl tRNA synthetase-IN-2
Aminoacyl tRNA synthetase-IN-2 (Compound 14) is an aminoacyl-tRNA synthetase (aaRS) inhibitor. Aminoacyl tRNA synthetase-IN-2 can be used for development of a new family of antibiotics[1].
Product Specifications
CAS Number
93218-59-8
UNSPSC
12352005
Target
Aminoacyl-tRNA Synthetase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/aminoacyl-trna-synthetase-in-2.html
Solubility
10 mM in DMSO
Smiles
O=C(O)[C@H](NC([C@@H](N)CO)=O)[C@@H]([C@@H]1[C@H](O)[C@@H](O)[C@H](N(C(N2C)=O)C=CC2=O)S1)O
Molecular Formula
C15H22N4O9S
Molecular Weight
434.42
References & Citations
[1]Gadakh B, et al. Synthesis and structural insights into the binding mode of the albomycin δ1 core and its analogues in complex with their target aminoacyl-tRNA synthetase. Bioorg Med Chem. 2020 Sep 1;28 (17) :115645.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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