ChemR23-IN-4
ChemR23-IN-4 (Compound 13) is a potent and orally efficacious ChemR23 inhibitor with an IC50 of 17 nM against human ChemR23[1].
Product Specifications
CAS Number
2465085-23-6
UNSPSC
12352005
Target
Chemerin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/chemr23-in-4.html
Solubility
10 mM in DMSO
Smiles
CCCCN([C@@H](C1=CC=C(C=C1)C2=CC=CC=C2C3=NN=NN3)C)C4=NC5=C(O4)C=CC=C5C(O)=O
Molecular Formula
C27H26N6O3
Molecular Weight
482.53
References & Citations
[1]Imaizumi T, et al. The design, synthesis and evaluation of 2-aminobenzoxazole analogues as potent and orally efficacious ChemR23 inhibitors. Bioorg Med Chem. 2020 Sep 1;28 (17) :115622.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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