KRAS G12C inhibitor 53

[2761968-93-6]

12352005

Ras

Reference compound

GPCR/G Protein; MAPK/ERK Pathway

Cancer-Kinase/protease

Cancer

https://www.medchemexpress.com/kras-g12c-inhibitor-53.html

10 mM in DMSO

C=CC(N1CC(C1)N2N=NC3=C2C4=CC(Cl)=C(C(F)=C4N=C3)C5=C(C=CC=C5O)F)=O

C21H14ClF2N5O2

441.82

[1]Youxi CHEN, et al. Heterocyclic derivative and preparation method therefor and use thereof. WO2022037631A1.

Room temperature

Reference compound1

No Development Reported

K-Ras