KRAS G12C inhibitor 53
KRAS G12C inhibitor 53 (Compound 1) is a KRAS G12C inhibitor[1].
Product Specifications
CAS Number
[2761968-93-6]
UNSPSC
12352005
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/kras-g12c-inhibitor-53.html
Solubility
10 mM in DMSO
Smiles
C=CC(N1CC(C1)N2N=NC3=C2C4=CC(Cl)=C(C(F)=C4N=C3)C5=C(C=CC=C5O)F)=O
Molecular Formula
C21H14ClF2N5O2
Molecular Weight
441.82
References & Citations
[1]Youxi CHEN, et al. Heterocyclic derivative and preparation method therefor and use thereof. WO2022037631A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
K-Ras
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