KRAS G12C inhibitor 53

KRAS G12C inhibitor 53 (Compound 1) is a KRAS G12C inhibitor[1].

Product Specifications

CAS Number

[2761968-93-6]

UNSPSC

12352005

Target

Ras

Type

Reference compound

Related Pathways

GPCR/G Protein; MAPK/ERK Pathway

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/kras-g12c-inhibitor-53.html

Solubility

10 mM in DMSO

Smiles

C=CC(N1CC(C1)N2N=NC3=C2C4=CC(Cl)=C(C(F)=C4N=C3)C5=C(C=CC=C5O)F)=O

Molecular Formula

C21H14ClF2N5O2

Molecular Weight

441.82

References & Citations

[1]Youxi CHEN, et al. Heterocyclic derivative and preparation method therefor and use thereof. WO2022037631A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

K-Ras

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