KRAS G12C inhibitor 50

[2760354-12-7]

12352005

Ras

Reference compound

GPCR/G Protein; MAPK/ERK Pathway

Cancer-Kinase/protease

Cancer

https://www.medchemexpress.com/kras-g12c-inhibitor-50.html

10 mM in DMSO

C=CC(N1CCN(C[C@@H]1CC#N)C2=NC(OC[C@@H]3CCCN3C)=NN4C(CC5=C6C=CC=CC6=CC=C5)=CN=C24)=O

C31H34N8O2

550.65

[1]Guoliang Zhang, et al. Imidazotriazine and pyrrolopyrimidine derivatives as kras g12c inhibitors. WO2022028492A1.

Room temperature

Reference compound1

No Development Reported

K-Ras