KRAS G12C inhibitor 50
Product Specifications
UNSPSC Description
KRAS G12C inhibitor 50 (Example 4) is a KRAS G12C inhibitor with an IC50 of 46.7 nM[1].
Target Antigen
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein;MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/kras-g12c-inhibitor-50.html
Solubility
10 mM in DMSO
Smiles
C=CC(N1CCN(C[C@@H]1CC#N)C2=NC(OC[C@@H]3CCCN3C)=NN4C(CC5=C6C=CC=CC6=CC=C5)=CN=C24)=O
Molecular Weight
550.65
References & Citations
[1]Guoliang Zhang, et al. Imidazotriazine and pyrrolopyrimidine derivatives as kras g12c inhibitors. WO2022028492A1.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-147631/KRAS-G12C-inhibitor-50-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-147631/
Clinical Information
No Development Reported
CAS Number
2760354-12-7
Curated Selection
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