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FGFR-IN-5

FGFR-IN-5 is a potent inhibitor of FGFR. Fibroblast growth factor receptor (FGFR) is a tyrosine kinase receptor that binds to fibroblast growth factor ligands. FGFR-IN-5 has the potential for the research of cancer diseases (extracted from patent WO2022042612A1, compound 3) [1]. FGFR-IN-5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Product Specifications

CAS Number

2762750-70-7

UNSPSC

12352005

Target

FGFR

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/fgfr-in-5.html

Solubility

10 mM in DMSO

Smiles

C=CC(N1CC[C@@H](C1)N2C=C(C3=C2C(NN=C3N)=O)C#CC4=CC5=C(OC(C6CC6)=N5)C=C4)=O

Molecular Formula

C25H22N6O3

Molecular Weight

454.48

References & Citations

[1]Haibin Deng, et al. Dihydropyrrolo[2,3-d]pyridazin-7-one derivative, preparation method therefor, and application thereof. Patent WO2022042612A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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