PI3K/mTOR Inhibitor-6
PI3K/mTOR Inhibitor-6 (Compound 19c) is a potent and dual inhibitor of PI3K/mTOR. PI3K/mTOR Inhibitor-6 displays better stability in artificial gastric fluids than gedatolisib. PI3K/mTOR Inhibitor-6 significantly suppresses the PI3K/Akt/mTOR signaling pathway at 10 μM. PI3K/mTOR Inhibitor-6 has the potential for the research of cancer diseases[1].
Product Specifications
CAS Number
2456295-59-1
UNSPSC
12352005
Target
MTOR; PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pi3k-mtor-inhibitor-6.html
Solubility
10 mM in DMSO
Smiles
O=C([C@@H]1N(C(C2=CC=C3C(NC(NC4=CC=C(C5=NC(N6CCOCC6)=NC(N7CCOCC7)=N5)C=C4)=N3)=C2)=O)CCC1)N
Molecular Formula
C30H34N10O4
Molecular Weight
598.66
References & Citations
[1]Wang L, et al. Design, synthesis and bioevaluation of novel substituted triazines as potential dual PI3K/mTOR inhibitors. Eur J Med Chem. 2020 Oct 15;204:112637
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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