CDK7-IN-16
CDK7-IN-16 (compound 9) is a potent CDK 7 inhibitor with an IC50 range of 1 ~ 10 nM. CDK7-IN-16 can be used for researching anticancer, especially the cancer with transcriptional dysregulation[1].
Product Specifications
CAS Number
[2765676-32-0]
UNSPSC
12352005
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cdk7-in-16.html
Solubility
10 mM in DMSO
Smiles
CS(=O)(NC1=C2NC=C(C2=CC=C1)C3=C(C=NC(N[C@H]4CCCNC4)=N3)C(F)(F)F)=O
Molecular Formula
C19H21F3N6O2S
Molecular Weight
454.47
References & Citations
[1]Pengguan Qiu, et al. Pyrimidinyl derivatives, method for the production thereof and use thereof. CN114249712A (compound 9)
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK7
Curated Selection
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