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CDK7-IN-16

Product Specifications

UNSPSC Description

CDK7-IN-16 (compound 9) is a potent CDK 7 inhibitor with an IC50 range of 1 ~ 10 nM. CDK7-IN-16 can be used for researching anticancer, especially the cancer with transcriptional dysregulation[1].

Target Antigen

CDK

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cdk7-in-16.html

Solubility

10 mM in DMSO

Smiles

CS(=O)(NC1=C2NC=C(C2=CC=C1)C3=C(C=NC(N[C@H]4CCCNC4)=N3)C(F)(F)F)=O

Molecular Weight

454.47

References & Citations

[1]Pengguan Qiu, et al. Pyrimidinyl derivatives, method for the production thereof and use thereof. CN114249712A (compound 9)

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-147601/CDK7-IN-16-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-147601/

Clinical Information

No Development Reported

CAS Number

2765676-32-0

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