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CDK7-IN-16

CDK7-IN-16 (compound 9) is a potent CDK 7 inhibitor with an IC50 range of 1 ~ 10 nM. CDK7-IN-16 can be used for researching anticancer, especially the cancer with transcriptional dysregulation[1].

Product Specifications

CAS Number

[2765676-32-0]

UNSPSC

12352005

Target

CDK

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cdk7-in-16.html

Solubility

10 mM in DMSO

Smiles

CS(=O)(NC1=C2NC=C(C2=CC=C1)C3=C(C=NC(N[C@H]4CCCNC4)=N3)C(F)(F)F)=O

Molecular Formula

C19H21F3N6O2S

Molecular Weight

454.47

References & Citations

[1]Pengguan Qiu, et al. Pyrimidinyl derivatives, method for the production thereof and use thereof. CN114249712A (compound 9)

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

CDK7

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