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CDK7-IN-14

CDK7-IN-14 is a potent inhibitor of CDK7. CDK7-IN-14 is a pyrimidinyl derivative compound. CDK7-IN-14 has the potential for the research of various cancers, especially the cancer with transcriptional dysregulation (extracted from patent CN114249712A, compound 3) [1].

Product Specifications

CAS Number

[2765676-49-9]

UNSPSC

12352005

Target

CDK

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cdk7-in-14.html

Solubility

10 mM in DMSO

Smiles

CP(C)(C1=C(C=CC2=C1NC=C2C3=NC(N[C@H]4CCC[C@@H](C4)N)=NC=C3C(F)(F)F)C#N)=O

Molecular Formula

C22H24F3N6OP

Molecular Weight

476.43

References & Citations

[1]Guanpeng Qiu, et al. Pyrimidinyl derivatives, method for the production thereof and use thereof. Patent CN114249712A.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-147598/CDK7-IN-14-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-147598/

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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