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CD73-IN-10

CD73-IN-10 is a potent inhibitor of CD73. CD73 can catalyze the production of adenosine from extracellular 5'-phosphate adenosine (5'-AMP), and adenosine can induce immunosuppressive effects and promote tumor proliferation and/or metastasis. CD73-IN-10 be used for preparing a medicament for tumor-related diseases (extracted from patent WO2022068929A1, compound 4) [1].

Product Specifications

CAS Number

2766565-91-5

UNSPSC

12352005

Target

CD73

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/cd73-in-10.html

Solubility

10 mM in DMSO

Smiles

CN1N=CC2=C1N=C(C=C2[C@@H]3[C@@H](C(F)F)C3)C4=CNC(NC4=O)=O

Molecular Formula

C15H13F2N5O2

Molecular Weight

333.29

References & Citations

[1]Xuejun Zhang, et al. Pyrimidinedione compound and use thereof. Patent WO2022068929A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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