CD73-IN-10
Product Specifications
UNSPSC Description
CD73-IN-10 is a potent inhibitor of CD73. CD73 can catalyze the production of adenosine from extracellular 5'-phosphate adenosine (5'-AMP), and adenosine can induce immunosuppressive effects and promote tumor proliferation and/or metastasis. CD73-IN-10 be used for preparing a medicament for tumor-related diseases (extracted from patent WO2022068929A1, compound 4)[1].
Target Antigen
CD73
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cd73-in-10.html
Solubility
10 mM in DMSO
Smiles
CN1N=CC2=C1N=C(C=C2[C@@H]3[C@@H](C(F)F)C3)C4=CNC(NC4=O)=O
Molecular Weight
333.29
References & Citations
[1]Xuejun Zhang, et al. Pyrimidinedione compound and use thereof. Patent WO2022068929A1.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-147591/CD73-IN-10-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-147591/
Clinical Information
No Development Reported
CAS Number
2766565-91-5
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