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CD73-IN-9

CD73-IN-9 is a potent inhibitor of CD73. CD73 can catalyze the production of adenosine from extracellular 5'-phosphate adenosine (5'-AMP), and adenosine can induce immunosuppressive effects and promote tumor proliferation and/or metastasis. CD73-IN-9 be used for preparing a medicament for tumor-related diseases (extracted from patent WO2022068929A1, compound 2) [1].

Product Specifications

CAS Number

2766565-88-0

UNSPSC

12352005

Target

CD73

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/cd73-in-9.html

Solubility

10 mM in DMSO

Smiles

O=C1NC=C(C(N1)=O)C2=NN3C=NC=C3C([C@H]4C[C@@H]4C(F)F)=C2

Molecular Formula

C14H11F2N5O2

Molecular Weight

319.27

References & Citations

[1]Xuejun Zhang, et al. Pyrimidinedione compound and use thereof. Patent WO2022068929A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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