C5aR-IN-3
C5aR-IN-3 is a potent inhibitor of C5aR. Increased level of C5a has been associated with disorders such as autoimmune disorders and inflammatory disorders. C5aR-IN-3 has the potential for the research of inflammation diseases (extracted from patent WO2022028586A1, compound 89) [1].
Product Specifications
CAS Number
[2761048-50-2]
UNSPSC
12352005
Target
Complement System
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/c5ar-in-3.html
Solubility
10 mM in DMSO
Smiles
CC1=C(C(F)=CC=C1)C(N2[C@H]([C@H](C[C@H]3CCC[C@H]32)C(NC4=CC5=C(N(N=C5)C)C=C4)=O)C6=CC=C(C=C6)NC7CCOCC7)=O
Molecular Formula
C36H40FN5O3
Molecular Weight
609.73
References & Citations
[1]Gonghua Pan, et al. Compounds as c5ar inhibitors. Patent WO2022028586A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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