C5aR-IN-1
C5aR-IN-1 is a potent inhibitor of C5aR. Increased level of C5a has been associated with disorders such as autoimmune disorders and inflammatory disorders. C5aR-IN-1 has the potential for the research of inflammation diseases (extracted from patent WO2022028586A1, compound 47) [1].
Product Specifications
CAS Number
2761048-02-4
UNSPSC
12352005
Target
Complement System
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/c5ar-in-1.html
Solubility
10 mM in DMSO
Smiles
CC1=CC=C(C=C1C(F)(F)F)NC([C@H]2C[C@H]3CCC[C@H]3N([C@H]2C4=CC=C(C=C4)NC5CCCC5)C(C6=C(C=CC=C6C)F)=O)=O
Molecular Formula
C36H39F4N3O2
Molecular Weight
621.71
References & Citations
[1]Gonghua Pan, et al. Compounds as c5ar inhibitors. Patent WO2022028586A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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