BTK-IN-14
BTK-IN-14 is a potent inhibitor of BTK. BTK plays an important role in signaling mediated by B cell antigen receptor (BCR) and Fcγreceptor (FcγR) in B cells and myeloid cells, respectively. BTK-IN-14 has the potential for the research of related diseases, especially autoimmune diseases, inflammatory diseases or cancer (extracted from patent WO2022057894A1, compound 1) [1].
Product Specifications
CAS Number
2764674-60-2
UNSPSC
12352005
Target
Btk
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/btk-in-14.html
Solubility
10 mM in DMSO
Smiles
C[C@H]1CN(C[C@@H](N1C2=CC=C(N=C2)NC3=CC(C4=CC=NC(N5C=CN6C(C5=O)=CC7=C6CC(C)(C7)C)=C4CO)=CN(C3=O)C)C)C8COC8
Molecular Formula
C38H44N8O4
Molecular Weight
676.81
References & Citations
[1] Guangxiu Dai, et al. Heteroaryl heterocyclic compounds and uses thereof. Patent WO2022057894A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Recombinant Burkholderia pseudomallei Proline--tRNA ligase (proS), partial
Recombinant Mycobacterium tuberculosis Response regulator mprA (mprA)
Recombinant Mycobacterium tuberculosis Response regulator mprA (mprA)
Recombinant Mycobacterium tuberculosis Response regulator mprA (mprA)