BTK-IN-11
BTK-IN-11 is a potent inhibitor of BTK. BTK plays an important role in signaling mediated by B cell antigen receptor (BCR) and Fcγreceptor (FcγR) in B cells and myeloid cells, respectively. BTK-IN-11 has the potential for the research of related diseases, especially autoimmune diseases, inflammatory diseases or cancer (extracted from patent WO2022063101A1, compound Z2) [1].
Product Specifications
CAS Number
[2765852-46-6]
UNSPSC
12352005
Target
Btk
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/btk-in-11.html
Solubility
10 mM in DMSO
Smiles
CN1CCC2(NC3=C4C(C(C5=CC=C(C=C5Cl)OC6=CC=CC=C6)=O)=CNC4=NC=C3NC2=O)C1
Molecular Formula
C26H22ClN5O3
Molecular Weight
487.94
References & Citations
[1]Fusheng Zhou, et al. Aroyl substituted tricyclic compound, preparation method therefor and use thereof. Patent WO2022063101A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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