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BTK-IN-11

BTK-IN-11 is a potent inhibitor of BTK. BTK plays an important role in signaling mediated by B cell antigen receptor (BCR) and Fcγreceptor (FcγR) in B cells and myeloid cells, respectively. BTK-IN-11 has the potential for the research of related diseases, especially autoimmune diseases, inflammatory diseases or cancer (extracted from patent WO2022063101A1, compound Z2) [1].

Product Specifications

CAS Number

[2765852-46-6]

UNSPSC

12352005

Target

Btk

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/btk-in-11.html

Solubility

10 mM in DMSO

Smiles

CN1CCC2(NC3=C4C(C(C5=CC=C(C=C5Cl)OC6=CC=CC=C6)=O)=CNC4=NC=C3NC2=O)C1

Molecular Formula

C26H22ClN5O3

Molecular Weight

487.94

References & Citations

[1]Fusheng Zhou, et al. Aroyl substituted tricyclic compound, preparation method therefor and use thereof. Patent WO2022063101A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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