BTK-IN-11
BTK-IN-11 is a potent inhibitor of BTK. BTK plays an important role in signaling mediated by B cell antigen receptor (BCR) and Fcγreceptor (FcγR) in B cells and myeloid cells, respectively. BTK-IN-11 has the potential for the research of related diseases, especially autoimmune diseases, inflammatory diseases or cancer (extracted from patent WO2022063101A1, compound Z2) [1].
Product Specifications
CAS Number
2765852-46-6
UNSPSC
12352005
Target
Btk
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/btk-in-11.html
Solubility
10 mM in DMSO
Smiles
CN1CCC2(NC3=C4C(C(C5=CC=C(C=C5Cl)OC6=CC=CC=C6)=O)=CNC4=NC=C3NC2=O)C1
Molecular Formula
C26H22ClN5O3
Molecular Weight
487.94
References & Citations
[1]Fusheng Zhou, et al. Aroyl substituted tricyclic compound, preparation method therefor and use thereof. Patent WO2022063101A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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