Axl-IN-7
Axl-IN-7 (Chemie 22) is a potent AXL inhibitor. Axl-IN-7 can be used for Axl-related diseases research, for example cancers (such as acute myeloid leukemia, melanoma, breast cancer, pancreatic cancer, and glial tumors), renal disease, immune system disorders, and cardiovascular disease[1].
Product Specifications
CAS Number
1770821-83-4
UNSPSC
12352005
Target
TAM Receptor
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/axl-in-7.html
Solubility
10 mM in DMSO
Smiles
NC1=C2C(C3=CC=C(C=C3)NC(C4=CC=CN(C4=O)C5=CC=CC=C5)=O)=CN(C2=NC=N1)C6CCCC6
Molecular Formula
C29H26N6O2
Molecular Weight
490.56
References & Citations
[1]Longzhi Quansi, et al. Pyrrolo pyrimidine derivative. WO2015068767A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Axl
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