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ATR-IN-17

ATR-IN-17 (compound 88) is a potent ATR kinase inhibitor. ATR-IN-17 shows good anticancer activity in LoVo cells, with an IC50 of 1 nM[1].

Product Specifications

CAS Number

2761194-15-2

UNSPSC

12352005

Target

ATM/ATR

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; PI3K/Akt/mTOR

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/atr-in-17.html

Solubility

10 mM in DMSO

Smiles

CC1=NN=C(C1)C2=NSC3=C2N=C(C=C3C4(CCCCC4)C(N)=O)N5CCOC[C@H]5C

Molecular Formula

C22H28N6O2S

Molecular Weight

440.56

References & Citations

[1]Bo Shan, et al. Atr inhibitors and uses thereof. WO2022028598A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

ATR

Frequently Asked Questions

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