ATR-IN-17
ATR-IN-17 (compound 88) is a potent ATR kinase inhibitor. ATR-IN-17 shows good anticancer activity in LoVo cells, with an IC50 of 1 nM[1].
Product Specifications
CAS Number
[2761194-15-2]
UNSPSC
12352005
Target
ATM/ATR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/atr-in-17.html
Solubility
10 mM in DMSO
Smiles
CC1=NN=C(C1)C2=NSC3=C2N=C(C=C3C4(CCCCC4)C(N)=O)N5CCOC[C@H]5C
Molecular Formula
C22H28N6O2S
Molecular Weight
440.56
References & Citations
[1]Bo Shan, et al. Atr inhibitors and uses thereof. WO2022028598A1.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-147569/ATR-IN-17-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-147569/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ATR
Curated Selection
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