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ATR-IN-16

ATR-IN-16 (compound 46) is a potent ATR kinase inhibitor. ATR-IN-16 shows good anticancer activity in LoVo cells, with an IC50 of 410 nM[1].

Product Specifications

CAS Number

2756589-62-3

UNSPSC

12352005

Target

ATM/ATR

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; PI3K/Akt/mTOR

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/atr-in-16.html

Solubility

10 mM in DMSO

Smiles

CC1=NNC(NC2=CC(C3=C(C=NN3C)C)=CC(N4CCOC[C@H]4C)=N2)=C1

Molecular Formula

C19H25N7O

Molecular Weight

367.45

References & Citations

[1]Bo Shan, et al. Atr inhibitors and uses thereof. WO2022002245A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

ATR

Frequently Asked Questions

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