ATR-IN-13
ATR-IN-13 (compound A9) is a potent ATR kinase inhibitor, with an IC50 of 2 nM. ATR-IN-13 can be used for ATR kinase mediated diseases research, such as proliferative diseases and cancer[1].
Product Specifications
CAS Number
2758113-84-5
UNSPSC
12352005
Target
ATM/ATR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/atr-in-13.html
Solubility
10 mM in DMSO
Smiles
CC1=NN(C(C)=C1C2=CC(N3CCOC[C@H]3C)=NC4=C(C=NN24)C5=CC=NN5)C6=CC(F)=CN=C6
Molecular Formula
C24H24FN9O
Molecular Weight
473.51
References & Citations
[1]Xiangling Zheng, et al. Pyrazolopyrimidine compounds as ATR kinase inhibitors. CN113929688A.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ATR
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