A1AR antagonist 5
Product Specifications
UNSPSC Description
A1AR antagonist 5 (compound 20) is a potent and selective A1AR (A1 adenosine receptor) antagonist, with a pIC50 of 5.83 and a pKi of 6.11[1].
Target Antigen
Adenosine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/a1ar-antagonist-5.html
Solubility
10 mM in DMSO
Smiles
O=C1NC(N2CCCC2)=NC3=C1C(C4=CC=C(C=C4)Cl)=CC=N3
Molecular Weight
326.78
References & Citations
[1]Wei Y, et al. Identification of new potent A1 adenosine receptor antagonists using a multistage virtual screening approach. Eur J Med Chem. 2020 Feb 1;187:111936.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-147544/A1AR-antagonist-5-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-147544/
Clinical Information
No Development Reported
CAS Number
1030509-01-3
Curated Selection
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