Antitumor agent-64
Antitumor agent-64 (Compound 8d) is a diosgenin derivative. Antitumor agent-64 exhibits potent cytotoxic activity against A549 cell line. Antitumor agent-64 induces A549 cells apoptosis via the mitochondria-related pathway[1].
Product Specifications
CAS Number
2396562-55-1
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antitumor-agent-64.html
Solubility
10 mM in DMSO
Smiles
C[C@@]12[C@]3([H])[C@](O[C@@H]([C@H]3C)CC[C@H](C4=NN=C(C5=CN=CC=C5)S4)C)([H])C[C@@]1([H])[C@@]6([H])[C@]([C@@]7(C(C[C@H](CC7)OC(C)=O)=CC6)C)([H])CC2
Molecular Formula
C35H47N3O3S
Molecular Weight
589.83
References & Citations
[1]Zhang J, et al. Novel diosgenin derivatives containing 1,3,4-oxadiazole/thiadiazole moieties as potential antitumor agents: Design, synthesis and cytotoxic evaluation. Eur J Med Chem. 2020 Jan 15;186:111897.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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