Antileishmanial agent-9
Antileishmanial agent-9 (compound 16c) has potent and selective activity against Leishmania donovani (L. donovani) with an IC50 value of 4.01 μM. Antileishmanial agent-9 has relatively low cytotoxicity in L-6 cells (IC50 = 40.1 μM) [1].
Product Specifications
CAS Number
2477608-91-4
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antileishmanial-agent-9.html
Solubility
10 mM in DMSO
Smiles
O=C(OC(C)(C)C)/C=C/C1=CC=C(OC(C2=CC=C(OC)C=C2)C3C)C3=C1
Molecular Formula
C23H26O4
Molecular Weight
366.45
References & Citations
[1]Bernal FA, et al. (±) -trans-2-phenyl-2,3-dihydrobenzofurans as leishmanicidal agents: Synthesis, in vitro evaluation and SAR analysis. Eur J Med Chem. 2020;205:112493.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Leishmania
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