Antileishmanial agent-8
Antileishmanial agent-8 (compound 18) has potent and selective activity against Leishmania donovani (L. donovani) with an IC50 value of 5.64 μM. Antileishmanial agent-8 has relatively low cytotoxicity in L-6 cells (IC50=73.9 μM) [1].
Product Specifications
CAS Number
2477608-96-9
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antileishmanial-agent-8.html
Solubility
10 mM in DMSO
Smiles
O=C(O)/C=C/C1=CC=C(OC(C2=CC=C(O)C=C2)C3C)C3=C1
Molecular Formula
C18H16O4
Molecular Weight
296.32
References & Citations
[1]Bernal FA, et al. (±) -trans-2-phenyl-2,3-dihydrobenzofurans as leishmanicidal agents: Synthesis, in vitro evaluation and SAR analysis. Eur J Med Chem. 2020;205:112493.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Leishmania
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
