Antileishmanial agent-6
Antileishmanial agent-6 (compound 8m) is a potent antileishmanial agent. Antileishmanial agent-6 shows antileishmanial and cytotoxic activity against Leishmania donovani and L-6, with IC50 values of 0.54 and 10.2 μM, respectively[1].
Product Specifications
CAS Number
9007-83-4
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antileishmanial-agent-6.html
Solubility
10 mM in DMSO
Smiles
O=C(C1C(C2=CC=C(O)C(O)=C2)OC3=C(O)C=C(/C=C/C(OC(C)C)=O)C=C13)OC(C)C
Molecular Formula
C24H26O8
Molecular Weight
442.46
References & Citations
[1]Bernal FA, et al. (±) -trans-2-phenyl-2,3-dihydrobenzofurans as leishmanicidal agents: Synthesis, in vitro evaluation and SAR analysis. Eur J Med Chem. 2020 Nov 1;205:112493.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Leishmania
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