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MGluR2 modulator 4

MGluR2 modulator 4 (compound 47) is a potent mGluR2 positive allosteric modulator with an EC50 value of 0.8 μM. mGluR2 modulator 4 can be used for researching antipsychotic[1].

Product Specifications

CAS Number

2582758-47-0

UNSPSC

12352005

Target

MGluR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/mglur2-modulator-4.html

Solubility

10 mM in DMSO

Smiles

BrC1=CC=C(C=C1)CCN2CCN3C4=CC=CC=C4N=C3C2

Molecular Formula

C18H18BrN3

Molecular Weight

356.26

References & Citations

[1]Szabó G, et al. Discovery of dihydropyrazino-benzimidazole derivatives as metabotropic glutamate receptor-2 (mGluR2) positive allosteric modulators (PAMs) . Eur J Med Chem. 2020;186:111881.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

MGluR2

Frequently Asked Questions

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