SARS-CoV-2-IN-21

SARS-CoV-2-IN-21 (compound 10), a penicillin sulfone benzyl C6 derivative, is a potent SARS-CoV-2 main protease inhibitor, with an IC50 of 5.3 μM. SARS-CoV-2-IN-21 can be used for COVID-19 research[1].

Product Specifications

CAS Number

[89971-88-0]

UNSPSC

12352005

Target

SARS-CoV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/sars-cov-2-in-21.html

Solubility

10 mM in DMSO

Smiles

O=C1[C@H]([C@@H]2N1[C@H](C(C)(S2(=O)=O)C)C(OCC3=CC=CC=C3)=O)NC(COC4=CC=CC=C4)=O

Molecular Formula

C23H24N2O7S

Molecular Weight

472.51

References & Citations

[1]Malla TR, et al. Penicillin Derivatives Inhibit the SARS-CoV-2 Main Protease by Reaction with Its Nucleophilic Cysteine. J Med Chem. 2022 May 12:acs.jmedchem.1c02214.