PPARγ agonist 7
PPARγ agonist 7 (Compound 3a) is a potent and selective agonist of PPARγ. PPARγ agonist 7 promotes adiponectin production in human bone marrow mesenchymal stem cells (hBM-MSCs) as a novel PPARγ full agonist (EC50, 4.34 μM) [1].
Product Specifications
CAS Number
2569295-93-6
UNSPSC
12352005
Target
PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/pparγ-agonist-7.html
Solubility
10 mM in DMSO
Smiles
C[C@@H]1OC(/C([C@@H]1O)=C/CCCCCCCC/C=C2C(O[C@H]([C@H]/2O)C)=O)=O
Molecular Formula
C20H30O6
Molecular Weight
366.45
References & Citations
[1]Ahn S, et al. Novel linked butanolide dimer compounds increase adiponectin production during adipogenesis in human mesenchymal stem cells through peroxisome proliferator-activated receptor γ modulation. Eur J Med Chem. 2020 Feb 1;187:111969.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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