TRβ agonist 3
TRβ agonist 3 (Compound 3) is a potent agonist of TRβ. TRβ agonist 3 reduces lipid accumulation in HepG2 and promote lipolysis with comparable effects. TRβ agonist 3 is a new potential TRβ-selective thyromimetics[1].
Product Specifications
CAS Number
2411099-46-0
UNSPSC
12352005
Target
Thyroid Hormone Receptor
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/trβ-agonist-3.html
Solubility
10 mM in DMSO
Smiles
CC1=CC(OCC(O)=O)=CC(C)=C1CC2=CC(C(C)C)=C(C=C2)N
Molecular Formula
C20H25NO3
Molecular Weight
327.42
References & Citations
[1]Runfola M, et al. Design, synthesis and biological evaluation of novel TRβ selective agonists sustained by ADME-toxicity analysis. Eur J Med Chem. 2020 Feb 15;188:112006.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
GTR15145785 1 Vial
Lentiviral mouse Opn1mw shRNA (UAS) - Lentiviral mouse Opn1mw shRNA (UAS, GFP) (100)
Sign In for Pricing
View Details 
VAng-Yyj1277-50gEcoli 50 µg (E. coli)
Recombinant Mycobacterium Avium MAV_1058 Protein（aa 1-304)
Sign In for Pricing
View Details NBP2-74422C 0.1 mL
Mouse Monoclonal Syntrophin alpha 1 Antibody (OTI1H10) [DyLight 650]
Sign In for Pricing
View Details 
CV-3 1 PC/Pack - 50 Packs/Bag - 20 Bags/CTN
Explosion-proof Cryogenic Vial (Individually Wrapped)
Sign In for Pricing
View Details